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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2729
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gpx1
Name: glutathione peroxidase 1
Acc ID: CHEBI:6842
Term: methoxychlor
Definition: An organochlorine insecticide that has formula C16H15Cl3O2.
Chemical ID: MESH:D008731
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gpx1decreases expressionISOGpx1 (Mus musculus)6480464CTDMethoxychlor results in decreased expression of GPX1 mRNAPMID:16807286
Gpx1multiple interactionsISOGpx1 (Mus musculus)6480464CTDMethoxychlor results in decreased expression of and results in decreased activity of GPX1 proteinPMID:16890261
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