GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gfap | decreases expression | EXP | | 6480464 | CTD | troglitazone results in decreased expression of GFAP mRNA; troglitazone results in decreased expression of GFAP protein | PMID:24481447 | Gfap | multiple interactions | EXP | | 6480464 | CTD | [Troglitazone results in increased phosphorylation of and results in increased activity of PPARG protein] which results in decreased expression of GFAP protein; CR8 compound inhibits the reaction [Troglitazone results in decreased expression of GFAP protein]; Troglitazone inhibits the reaction [Lipopolysaccharides results in increased expression of GFAP protein]; Troglitazone promotes the reaction [PPARG protein binds to GFAP promoter] | PMID:24481447 | | ||||||||||||||||||||||
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