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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2645
Species: Rattus norvegicus
RGD Object: Gene
Symbol: G6pd
Name: glucose-6-phosphate dehydrogenase
Acc ID: CHEBI:64090
Term: tert-butyl hydroperoxide
Definition: An alkyl hydroperoxide in which the alkyl group is tert-butyl. It is widely used in a variety of oxidation processes.
Chemical ID: MESH:D020122
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
G6pdincreases activityEXP 6480464CTDtert-Butylhydroperoxide results in increased activity of G6PD proteinPMID:16928893
G6pddecreases activityISOG6PD (Homo sapiens)6480464CTDtert-Butylhydroperoxide results in decreased activity of G6PD proteinPMID:12628296
G6pdincreases activityISOG6pdx (Mus musculus)6480464CTDtert-Butylhydroperoxide results in increased activity of G6PD proteinPMID:15336504
G6pdincreases activityISOG6PD (Homo sapiens)6480464CTDtert-Butylhydroperoxide results in increased activity of G6PD proteinPMID:15336504
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