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GENE - TERM ANNOTATION REPORT

RGD ID: 2643
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Xrcc6
Name: X-ray repair cross complementing 6
Acc ID: GO:0043564
Term: Ku70:Ku80 complex
Definition: Heterodimeric protein complex composed of a 70 kDa and a 80 kDa subunit, binds DNA through a channel formed by the heterodimer. Functions in DNA double stranded break repair, chromosome maintenance, transcription regulation, V(D)J recombination, and activation of DNA-PK.
Definition Source(s): PMID:12518983
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Xrcc6part_ofISOXRCC6 (Homo sapiens)1624291RGD PMID:11493912 PMID:20383123 PMID:24095731 PMID:26359349

PMID:11493912 PMID:20383123 PMID:24095731 PMID:26359349
Xrcc6part_ofIBAFB:FBgn0011774 or PANTHER:PTN000288287 or SGD:S000004712 or SGD:S000004897 or UniProtKB:P12956 or UniProtKB:P13010 or dictyBase:DDB_G0286069 or dictyBase:DDB_G02863031600115GO_CentralGO_REF:0000033

GO_REF:0000033
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