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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2617
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fkbp1a
Name: FKBP prolyl isomerase 1A
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fkbp1adecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of FKBP1A mRNAPMID:30816183
Fkbp1aincreases expressionEXP 6480464CTDbisphenol A results in increased expression of FKBP1A mRNAPMID:25181051
Fkbp1amultiple interactionsEXP 6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of FKBP1A mRNAPMID:36041667
Fkbp1aaffects expressionISOFKBP1A (Homo sapiens)6480464CTDbisphenol A affects the expression of FKBP1A mRNAPMID:30903817
Fkbp1adecreases expressionISOFKBP1A (Homo sapiens)6480464CTDbisphenol A results in decreased expression of FKBP1A mRNAPMID:29275510
Fkbp1adecreases expressionISOFkbp1a (Mus musculus)6480464CTDbisphenol A results in decreased expression of FKBP1A mRNAPMID:33221593
Fkbp1adecreases methylationISOFkbp1a (Mus musculus)6480464CTDbisphenol A results in decreased methylation of FKBP1A promoterPMID:27312807
Fkbp1aincreases expressionISOFKBP1A (Homo sapiens)6480464CTDbisphenol A results in increased expression of FKBP1A proteinPMID:37567409
Fkbp1amultiple interactionsISOFKBP1A (Homo sapiens)6480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of FKBP1A mRNAPMID:28628672
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