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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2587
Species: Rattus norvegicus
RGD Object: Gene
Symbol: F3
Name: coagulation factor III, tissue factor
Acc ID: CHEBI:2504
Term: aflatoxin B1
Definition: An aflatoxin having a tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene skeleton with oxygen functionality at positions 1, 4 and 11.
Chemical ID: MESH:D016604
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
F3increases expressionEXP 6480464CTDAflatoxin B1 results in increased expression of F3 mRNAPMID:33354967
F3affects expressionISOF3 (Homo sapiens)6480464CTDAflatoxin B1 affects the expression of F3 proteinPMID:20106945
F3decreases expressionISOF3 (Mus musculus)6480464CTDAflatoxin B1 results in decreased expression of F3 mRNAPMID:19770486
F3increases expressionISOF3 (Homo sapiens)6480464CTDAflatoxin B1 results in increased expression of F3 mRNAPMID:22100608
F3increases methylationISOF3 (Homo sapiens)6480464CTDAflatoxin B1 results in increased methylation of F3 genePMID:27153756
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