GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ephx1 | decreases expression | EXP | | 6480464 | CTD | 4-vinyl-1-cyclohexene dioxide results in decreased expression of EPHX1 mRNA | PMID:8806858 | Ephx1 | increases expression | EXP | | 6480464 | CTD | 4-vinyl-1-cyclohexene dioxide results in increased expression of EPHX1 mRNA; 4-vinyl-1-cyclohexene dioxide results in increased expression of EPHX1 protein | PMID:22061827 PMID:8806858 | Ephx1 | increases metabolic processing | EXP | | 6480464 | CTD | EPHX1 protein results in increased metabolism of 4-vinyl-1-cyclohexene dioxide | PMID:22061827 | Ephx1 | multiple interactions | EXP | | 6480464 | CTD | [cyclohexene oxide results in decreased activity of EPHX1 protein] which results in increased susceptibility to 4-vinyl-1-cyclohexene dioxide | PMID:22061827 | Ephx1 | increases expression | ISO | Ephx1 (Mus musculus) | 6480464 | CTD | 4-vinyl-1-cyclohexene dioxide results in increased expression of EPHX1 mRNA; 4-vinyl-1-cyclohexene dioxide results in increased expression of EPHX1 protein | PMID:22061827 | Ephx1 | increases metabolic processing | ISO | Ephx1 (Mus musculus) | 6480464 | CTD | EPHX1 protein results in increased metabolism of 4-vinyl-1-cyclohexene dioxide | PMID:22061827 | | ||||||||||||||||||||||
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