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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2521
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Drd3
Name: dopamine receptor D3
Acc ID: CHEBI:34372
Term: 4,4'-sulfonyldiphenol
Definition: A sulfone that is diphenyl sulfone in which both of the para hydrogens have been replaced by hydroxy groups.
Chemical ID: MESH:C543008
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Drd3decreases expressionEXP 6480464CTDbisphenol S results in decreased expression of DRD3 mRNAPMID:26186136
Drd3increases expressionISODrd3 (Mus musculus)6480464CTDbisphenol S results in increased expression of DRD3 mRNAPMID:33297965
Drd3increases methylationISODrd3 (Mus musculus)6480464CTDbisphenol S results in increased methylation of DRD3 exonPMID:33297965
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