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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2493
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ace
Name: angiotensin I converting enzyme
Acc ID: CHEBI:35459
Term: diisononyl phthalate
Definition: The diisononyl ester of benzene-1,2-dicarboxylic acid.
Chemical ID: MESH:C012125
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aceincreases expressionISOAce (Mus musculus)6480464CTDdiisononyl phthalate results in increased expression of ACE proteinPMID:30940551
Acemultiple interactionsISOAce (Mus musculus)6480464CTDdiisononyl phthalate promotes the reaction [Dexamethasone results in increased expression of ACE protein]; Enalapril inhibits the reaction [diisononyl phthalate promotes the reaction [Dexamethasone results in increased expression of ACE protein]]PMID:30940551
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