GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp7a1 | decreases expression | ISO | Cyp7a1 (Mus musculus) | 6480464 | CTD | Oleanolic Acid results in decreased expression of CYP7A1 mRNA; Oleanolic Acid results in decreased expression of CYP7A1 protein | PMID:23948738 PMID:37028458 | Cyp7a1 | multiple interactions | ISO | Cyp7a1 (Mus musculus) | 6480464 | CTD | GW 4064 inhibits the reaction [Oleanolic Acid results in decreased expression of CYP7A1 mRNA]; GW 4064 inhibits the reaction [Oleanolic Acid results in decreased expression of CYP7A1 protein]; HNF1A protein affects the reaction [SRT1720 inhibits the reaction [Oleanolic Acid results in decreased expression of CYP7A1 protein]]; SRT1720 inhibits the reaction [Oleanolic Acid results in decreased expression of CYP7A1 mRNA] | PMID:37028458 | |
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