GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp2e1 | decreases activity | EXP | | 6480464 | CTD | allyl sulfide results in decreased activity of CYP2E1 protein | PMID:30247689 PMID:7956723 | Cyp2e1 | decreases expression | EXP | | 6480464 | CTD | allyl sulfide results in decreased expression of CYP2E1 protein | PMID:16000231 PMID:7601153 PMID:8117321 | Cyp2e1 | increases activity | EXP | | 6480464 | CTD | allyl sulfide results in increased activity of CYP2E1 protein | PMID:15046820 | Cyp2e1 | increases expression | EXP | | 6480464 | CTD | allyl sulfide results in increased expression of CYP2E1 protein | PMID:8627517 | Cyp2e1 | multiple interactions | EXP | | 6480464 | CTD | allyl sulfide inhibits the reaction [1-bromopropane results in increased expression of CYP2E1]; allyl sulfide inhibits the reaction [CYP2E1 protein results in increased metabolism of 2,2-dichloro-1,1,1-trifluoroethane]; allyl sulfide inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol]; allyl sulfide inhibits the reaction [CYP2E1 protein results in increased metabolism of aniline]; allyl sulfide inhibits the reaction [CYP2E1 protein results in increased metabolism of Carbon Tetrachloride]; allyl sulfide inhibits the reaction [CYP2E1 protein results in increased metabolism of Dimethylnitrosamine]; allyl sulfide inhibits the reaction [Diethylnitrosamine results in decreased expression of and results in decreased activity of CYP2E1 protein]; allyl sulfide inhibits the reaction [Diethylnitrosamine results in decreased expression of CYP2E1 mRNA]; allyl sulfide inhibits the reaction [Ethanol results in increased activity of CYP2E1 protein]; allyl sulfide inhibits the reaction [Ethylene Chlorohydrin results in increased expression of CYP2E1 mRNA]; allyl sulfide inhibits the reaction [Ethylene Chlorohydrin results in increased expression of CYP2E1 protein]; allyl sulfide inhibits the reaction [Pyrazines results in increased activity of CYP2E1 protein]; allyl sulfide inhibits the reaction [Pyrazines results in increased expression of CYP2E1 protein] | PMID:20116195 PMID:23494807 PMID:30247689 PMID:31585129 PMID:7601153 PMID:7956723 PMID:8117321 | Cyp2e1 | decreases activity | ISO | CYP2E1 (Homo sapiens) | 6480464 | CTD | allyl sulfide results in decreased activity of CYP2E1 protein | PMID:15974642 PMID:17034788 PMID:18339364 | Cyp2e1 | decreases expression | ISO | Cyp2e1 (Mus musculus) | 6480464 | CTD | allyl sulfide results in decreased expression of CYP2E1 mRNA | PMID:33007364 | Cyp2e1 | multiple interactions | ISO | Cyp2e1 (Mus musculus) | 6480464 | CTD | allyl sulfide inhibits the reaction [[ethylene dichloride co-treated with Ethanol] results in increased expression of CYP2E1 protein]; allyl sulfide inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 mRNA]; allyl sulfide inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]; allyl sulfide inhibits the reaction [ethylene dichloride results in increased expression of CYP2E1 protein]; allyl sulfide inhibits the reaction [Valproic Acid results in increased expression of and results in decreased activity of CYP2E1 protein]; allyl sulfide inhibits the reaction [Valproic Acid results in increased expression of CYP2E1 mRNA]; allyl sulfide results in decreased expression of and results in decreased activity of CYP2E1 protein | PMID:21684301 PMID:22138249 PMID:27301210 PMID:33007364 PMID:37150348 | Cyp2e1 | multiple interactions | ISO | CYP2E1 (Homo sapiens) | 6480464 | CTD | [Propolis co-treated with allyl sulfide] inhibits the reaction [4-biphenylamine results in increased expression of CYP2E1 protein]; allyl sulfide inhibits the reaction [4-biphenylamine results in increased expression of CYP2E1 protein]; allyl sulfide inhibits the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]]; allyl sulfide inhibits the reaction [CYP2E1 protein promotes the reaction [Arachidonic Acid results in increased expression of KLF6 mRNA alternative form]]; allyl sulfide inhibits the reaction [CYP2E1 protein results in increased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid]]; allyl sulfide inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]; allyl sulfide inhibits the reaction [Valproic Acid results in increased expression of and results in increased activity of CYP2E1 protein]; allyl sulfide inhibits the reaction [Valproic Acid results in increased expression of CYP2E1 mRNA] | PMID:12086689 PMID:22138249 PMID:22486562 PMID:33007364 PMID:33847444 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |