GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp2e1 | increases expression | EXP | | 6480464 | CTD | Monocrotophos results in increased expression of CYP2E1 protein | PMID:21445290 | Cyp2e1 | increases activity | ISO | CYP2E1 (Homo sapiens) | 6480464 | CTD | Monocrotophos results in increased activity of CYP2E1 protein | PMID:22733800 | Cyp2e1 | increases expression | ISO | CYP2E1 (Homo sapiens) | 6480464 | CTD | Monocrotophos results in increased expression of CYP2E1 mRNA; Monocrotophos results in increased expression of CYP2E1 protein | PMID:22733800 | Cyp2e1 | multiple interactions | ISO | CYP2E1 (Homo sapiens) | 6480464 | CTD | [Monocrotophos co-treated with Cimetidine] results in increased expression of CYP2E1 protein; [Rifampin co-treated with Monocrotophos] results in increased activity of CYP2E1 protein; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP2E1 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP2E1 protein | PMID:22733800 | | ||||||||||||||||||||||
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