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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2475
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2e1
Name: cytochrome P450, family 2, subfamily e, polypeptide 1
Acc ID: CHEBI:30956
Term: trichloroacetic acid
Definition: A monocarboxylic acid that is acetic acid in which all three methyl hydrogens are substituted by chlorine.
Chemical ID: MESH:D014238
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2e1multiple interactionsISOCYP2E1 (Homo sapiens)6480464CTD[CYP2E1 protein results in increased oxidation of Tetrachloroethylene] which results in increased abundance of Trichloroacetic Acid; [CYP2E1 protein results in increased oxidation of Trichloroethylene] which results in increased abundance of Trichloroacetic AcidPMID:29897530
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