GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp2e1 | multiple interactions | EXP | | 6480464 | CTD | [2-dichlorobenzene analog co-treated with NADP] results in decreased activity of CYP2E1 protein; NADP promotes the reaction [Isoniazid results in decreased activity of CYP2E1 protein] | PMID:24713513 PMID:39047805 | Cyp2e1 | multiple interactions | ISO | Cyp2e1 (Mus musculus) | 6480464 | CTD | NADP promotes the reaction [Isoniazid results in decreased activity of CYP2E1 protein] | PMID:39047805 | Cyp2e1 | multiple interactions | ISO | CYP2E1 (Homo sapiens) | 6480464 | CTD | [acetylhydrazine co-treated with NADP] results in decreased activity of CYP2E1 protein; [hydrazine co-treated with NADP] results in decreased activity of CYP2E1 protein; [vinyl carbamate co-treated with NADP] inhibits the reaction [CYP2E1 protein results in decreased methylation of Dimethylnitrosamine]; NADP promotes the reaction [Isoniazid results in decreased activity of CYP2E1 protein] | PMID:11181492 PMID:39047805 | | ||||||||||||||||||||||
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