GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp2e1 | affects hydroxylation | ISO | Cyp2e1 (Mus musculus) | 6480464 | CTD | CYP2E1 protein affects the hydroxylation of Urethane | PMID:15879495 | Cyp2e1 | affects metabolic processing | ISO | Cyp2e1 (Mus musculus) | 6480464 | CTD | CYP2E1 protein affects the metabolism of Urethane | PMID:12704224 PMID:15879495 PMID:17979661 | Cyp2e1 | affects oxidation | ISO | Cyp2e1 (Mus musculus) | 6480464 | CTD | CYP2E1 protein affects the oxidation of Urethane | PMID:20205516 | Cyp2e1 | decreases metabolic processing | ISO | Cyp2e1 (Mus musculus) | 6480464 | CTD | CYP2E1 gene mutant form results in decreased metabolism of Urethane | PMID:12704224 | Cyp2e1 | decreases response to substance | ISO | Cyp2e1 (Mus musculus) | 6480464 | CTD | CYP2E1 gene mutant form results in decreased susceptibility to Urethane | PMID:17093202 | Cyp2e1 | increases oxidation | ISO | CYP2E1 (Homo sapiens) | 6480464 | CTD | CYP2E1 protein results in increased oxidation of Urethane | PMID:1664256 | Cyp2e1 | increases response to substance | ISO | Cyp2e1 (Mus musculus) | 6480464 | CTD | CYP2E1 protein results in increased susceptibility to Urethane | PMID:15790490 | Cyp2e1 | multiple interactions | ISO | Cyp2e1 (Mus musculus) | 6480464 | CTD | 1-aminobenzotriazole inhibits the reaction [CYP2E1 protein affects the metabolism of Urethane]; [Urethane co-treated with Ethanol] results in increased activity of CYP2E1 protein; CYP2E1 gene mutant form inhibits the reaction [Urethane affects the expression of MKI67 protein] | PMID:12704224 PMID:15582191 PMID:15790490 | | ||||||||||||||||||||||
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