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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2465
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2a3
Name: cytochrome P450, family 2, subfamily a, polypeptide 3
Acc ID: CHEBI:46680
Term: serpentine asbestos
Definition: null
Chemical ID: MESH:D017632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2a3decreases expressionISOCyp2a4 (Mus musculus)6480464CTDAsbestos, Serpentine results in decreased expression of CYP2A4 mRNAPMID:21514415
Cyp2a3multiple interactionsISOCyp2a4 (Mus musculus)6480464CTDSPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in decreased expression of CYP2A4 mRNA]PMID:21514415
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