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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2460
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp1b1
Name: cytochrome P450, family 1, subfamily b, polypeptide 1
Acc ID: CHEBI:5070
Term: flavanone
Definition: The simplest member of the class of flavanones that consists of flavan bearing an oxo substituent at position 4.
Chemical ID: MESH:C028610
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1b1increases expressionISOCyp1b1 (Mus musculus)6480464CTDflavanone analog results in increased expression of CYP1B1 mRNAPMID:31621310
Cyp1b1multiple interactionsISOCYP1B1 (Homo sapiens)6480464CTDflavanone binds to and results in decreased activity of CYP1B1 proteinPMID:21053930
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