GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp1a1 | decreases activity | ISO | CYP1A1 (Homo sapiens) | 6480464 | CTD | Eugenol results in decreased activity of CYP1A1 protein | PMID:17275817 | Cyp1a1 | decreases expression | ISO | CYP1A1 (Homo sapiens) | 6480464 | CTD | Eugenol results in decreased expression of CYP1A1 mRNA | PMID:20713136 | Cyp1a1 | increases expression | ISO | CYP1A1 (Homo sapiens) | 6480464 | CTD | Eugenol results in increased expression of CYP1A1 mRNA | PMID:22686307 PMID:29191726 | Cyp1a1 | multiple interactions | ISO | CYP1A1 (Homo sapiens) | 6480464 | CTD | [CYP1A1 protein co-treated with Copper] results in increased activity of Eugenol; Eugenol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 mRNA]; Eugenol inhibits the reaction [CYP1A1 protein results in increased metabolism of and results in increased activity of 9,10-Dimethyl-1,2-benzanthracene]; Eugenol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] | PMID:15576237 PMID:17275817 PMID:29191726 | |
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