GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp17a1 | decreases activity | EXP | | 6480464 | CTD | di-n-pentyl phthalate results in decreased activity of CYP17A1 protein | PMID:6829050 | Cyp17a1 | decreases expression | EXP | | 6480464 | CTD | di-n-pentyl phthalate results in decreased expression of CYP17A1 mRNA; di-n-pentyl phthalate results in decreased expression of CYP17A1 protein | PMID:22112501 PMID:25055962 PMID:26472102 PMID:33798595 PMID:33983380 | Cyp17a1 | multiple interactions | EXP | | 6480464 | CTD | [Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of CYP17A1 mRNA | PMID:25055962 | |
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