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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2366
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc2
Name: ATP binding cassette subfamily C member 2
Acc ID: CHEBI:27666
Term: actinomycin D
Definition: An actinomycin that has formula C62H86N12O16.
Chemical ID: MESH:D003609
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc2decreases response to substanceEXP 6480464CTDABCC2 protein results in decreased susceptibility to DactinomycinPMID:11455017
Abcc2multiple interactionsEXP 6480464CTDDactinomycin inhibits the reaction [sodium arsenite results in increased expression of ABCC2 mRNA]PMID:11408547
Abcc2multiple interactionsISOABCC2 (Homo sapiens)6480464CTDDactinomycin inhibits the reaction [Bucladesine results in increased expression of ABCC2 mRNA]PMID:26049102
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