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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2361
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Clcn2
Name: chloride voltage-gated channel 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Clcn2affects expressionEXP 6480464CTDbisphenol A affects the expression of CLCN2 mRNAPMID:25181051
Clcn2increases methylationEXP 6480464CTDbisphenol A results in increased methylation of CLCN2 genePMID:28505145
Clcn2multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Estradiol] results in increased expression of CLCN2 mRNAPMID:26496021
Clcn2increases expressionISOClcn2 (Mus musculus)6480464CTDbisphenol A results in increased expression of CLCN2 mRNAPMID:33221593 PMID:37894381
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