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Gene: Clcn2 (chloride channel, voltage-sensitive 2) Mus musculus
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Symbol: Clcn2
Name: chloride channel, voltage-sensitive 2
RGD ID: 736064
Description: Exhibits voltage-gated chloride channel activity. Involved in cell differentiation involved in salivary gland development and retina development in camera-type eye. Predicted to localize to dendrite; integral component of plasma membrane; and perikaryon. Is expressed in several structures, including central nervous system; gonad; hindlimb phalanx; notochord; and visual system. Used to study leukodystrophy. Human ortholog(s) of this gene implicated in idiopathic generalized epilepsy 11 and primary hyperaldosteronism. Orthologous to human CLCN2 (chloride voltage-gated channel 2); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AL118368; chloride channel 2; chloride channel protein 2; Clc; ClC-; ClC-2; Clc2; nmf24; nmf240
Orthologs:
Homo sapiens (human) : CLCN2 (chloride voltage-gated channel 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Clcn2 (chloride voltage-gated channel 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Clcn2 (chloride voltage-gated channel 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CLCN2 (chloride voltage-gated channel 2)
Canis lupus familiaris (dog) : CLCN2 (chloride voltage-gated channel 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Clcn2 (chloride voltage-gated channel 2)
Sus scrofa (pig) : CLCN2 (chloride voltage-gated channel 2)
Chlorocebus sabaeus (African green monkey) : CLCN2 (chloride voltage-gated channel 2)
Heterocephalus glaber (naked mole-rat) : Clcn2 (chloride voltage-gated channel 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391620,521,185 - 20,536,496 (-)NCBI
GRCm381620,702,435 - 20,717,746 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1620,702,964 - 20,717,746 (-)EnsemblGRCm38mm10GRCm38
MGSCv371620,703,039 - 20,716,709 (-)NCBIGRCm37mm9NCBIm37
MGSCv361620,616,509 - 20,629,657 (-)NCBImm8
Celera1621,268,322 - 21,281,991 (-)NCBICelera
Cytogenetic Map16A3- B1NCBI
cM Map1612.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on Clcn2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736064
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-11-03
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.