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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2322311
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Msh6
Name: mutS homolog 6
Acc ID: CHEBI:35456
Term: cadmium dichloride
Definition: A cadmium coordination entity in which cadmium(2+) and Cl(-) ions are present in the ratio 2:1. Although considered to be ionic, it has considerable covalent character to its bonding.
Chemical ID: MESH:D019256
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Msh6decreases expressionISOMSH6 (Homo sapiens)6480464CTDCadmium Chloride results in decreased expression of MSH6 mRNA; Cadmium Chloride results in decreased expression of MSH6 proteinPMID:28690196 PMID:38568856
Msh6multiple interactionsISOMSH6 (Homo sapiens)6480464CTDAcetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of MSH6 protein]PMID:28690196
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