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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2319
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdk1
Name: cyclin-dependent kinase 1
Acc ID: CHEBI:2979
Term: baicalein
Definition: A trihydroxyflavone with the hydroxy groups at positions C-5, -6 and -7.
Chemical ID: MESH:C006680
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdk1decreases phosphorylationISOCDK1 (Homo sapiens)6480464CTDbaicalein results in decreased phosphorylation of CDK1 proteinPMID:18025287
Cdk1multiple interactionsISOCDK1 (Homo sapiens)6480464CTDSB 203580 inhibits the reaction [baicalein results in decreased phosphorylation of CDK1 protein]; wortmannin promotes the reaction [baicalein results in decreased phosphorylation of CDK1 protein]PMID:18025287
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