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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2279
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cat
Name: catalase
Acc ID: CHEBI:7939
Term: parthenolide
Definition: A sesquiterpene lactone and active principle of Feverfew (Tanacetum parthenium).
Chemical ID: MESH:C002669
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Catmultiple interactionsEXP 6480464CTDparthenolide inhibits the reaction [Paclitaxel results in decreased activity of CAT protein]; parthenolide inhibits the reaction [Paclitaxel results in decreased expression of CAT mRNA]PMID:37949423
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