GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cat | decreases activity | EXP | | 6480464 | CTD | Indomethacin results in decreased activity of CAT protein | PMID:12566098 PMID:16397915 PMID:17351913 PMID:25926722 PMID:30252991 PMID:35752295 PMID:37483153 | Cat | decreases expression | EXP | | 6480464 | CTD | Indomethacin results in decreased expression of CAT mRNA; Indomethacin results in decreased expression of CAT protein | PMID:12500499 PMID:36868495 | Cat | decreases response to substance | EXP | | 6480464 | CTD | CAT protein results in decreased susceptibility to Indomethacin | PMID:1887894 | Cat | increases activity | EXP | | 6480464 | CTD | Indomethacin results in increased activity of CAT protein | PMID:16169175 PMID:17604372 PMID:17895592 PMID:18087811 PMID:18726076 PMID:19034656 PMID:19497431 | Cat | multiple interactions | EXP | | 6480464 | CTD | Allopurinol inhibits the reaction [Indomethacin results in decreased activity of CAT protein]; Amiodarone inhibits the reaction [Indomethacin results in increased activity of CAT protein]; Arginine inhibits the reaction [Indomethacin results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Indomethacin results in increased activity of CAT protein]; beta Carotene inhibits the reaction [Indomethacin results in decreased expression of CAT protein]; CAT protein inhibits the reaction [Hydrochloric Acid results in increased susceptibility to Indomethacin]; Curcumin inhibits the reaction [Indomethacin results in decreased activity of CAT protein]; Famotidine inhibits the reaction [Indomethacin results in decreased activity of CAT protein]; Famotidine inhibits the reaction [Indomethacin results in increased activity of CAT protein]; Indomethacin inhibits the reaction [Formaldehyde results in increased expression of CAT mRNA]; Indomethacin inhibits the reaction [Freund's Adjuvant results in decreased activity of CAT protein]; Indomethacin inhibits the reaction [Vanadates results in decreased activity of CAT protein]; Indomethacin promotes the reaction [morin inhibits the reaction [Freund's Adjuvant results in decreased activity of CAT protein]]; kolaviron inhibits the reaction [Indomethacin results in decreased activity of CAT protein]; Lansoprazole inhibits the reaction [Indomethacin results in increased activity of CAT protein]; Melatonin inhibits the reaction [Indomethacin results in decreased expression of CAT protein]; Mirtazapine inhibits the reaction [Indomethacin results in increased activity of CAT protein]; montelukast inhibits the reaction [Indomethacin results in increased activity of CAT protein]; morin promotes the reaction [Indomethacin inhibits the reaction [Freund's Adjuvant results in decreased activity of CAT protein]]; Quercetin promotes the reaction [Famotidine inhibits the reaction [Indomethacin results in decreased activity of CAT protein]]; Ranitidine inhibits the reaction [Indomethacin results in decreased activity of CAT protein]; Ranitidine inhibits the reaction [Indomethacin results in increased activity of CAT protein]; tianeptine inhibits the reaction [Indomethacin results in increased activity of CAT protein]; usnic acid inhibits the reaction [Indomethacin results in increased activity of CAT protein]; Zinc inhibits the reaction [Indomethacin results in decreased activity of CAT protein] | PMID:12500499 PMID:12566098 PMID:16169175 PMID:16397915 PMID:17351913 PMID:17895592 PMID:18087811 PMID:18726076 PMID:1887894 PMID:19034656 PMID:19497431 PMID:21983654 PMID:25698669 PMID:25926722 PMID:34431458 PMID:37483153 | Cat | multiple interactions | ISO | CAT (Homo sapiens) | 6480464 | CTD | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of CAT mRNA | PMID:28628672 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |