GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cat | decreases activity | EXP | | 6480464 | CTD | Chlorpyrifos results in decreased activity of CAT protein | PMID:22439320 PMID:27268782 PMID:28373059 PMID:29667781 PMID:30267645 PMID:30497708 PMID:33908150 PMID:34425170 PMID:34678318 PMID:35439518 | Cat | decreases expression | EXP | | 6480464 | CTD | Chlorpyrifos results in decreased expression of CAT mRNA; Chlorpyrifos results in decreased expression of CAT protein | PMID:31823260 PMID:32096903 | Cat | increases activity | EXP | | 6480464 | CTD | Chlorpyrifos results in increased activity of CAT protein | PMID:31400774 | Cat | increases expression | EXP | | 6480464 | CTD | Chlorpyrifos results in increased expression of CAT mRNA | PMID:17452286 PMID:19440498 | Cat | multiple interactions | EXP | | 6480464 | CTD | 3-(indol-3-yl)propionic acid inhibits the reaction [Chlorpyrifos results in decreased activity of CAT protein]; [Chlorpyrifos co-treated with carbendazim] results in decreased activity of CAT protein; [Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in increased activity of CAT protein; [Streptozocin co-treated with Chlorpyrifos] results in increased activity of CAT protein; Acetylcysteine inhibits the reaction [Chlorpyrifos results in decreased activity of CAT protein]; Berberine inhibits the reaction [Chlorpyrifos results in decreased activity of CAT protein]; Chlorpyrifos promotes the reaction [Streptozocin results in increased activity of CAT protein]; diphenyldiselenide inhibits the reaction [Chlorpyrifos results in decreased activity of CAT protein]; Eugenol inhibits the reaction [Chlorpyrifos results in decreased expression of CAT protein]; gingerol inhibits the reaction [Chlorpyrifos results in decreased activity of CAT protein]; Hesperidin inhibits the reaction [Chlorpyrifos results in decreased activity of CAT protein]; kaempferol inhibits the reaction [Chlorpyrifos results in decreased activity of CAT protein]; Plant Extracts inhibits the reaction [Chlorpyrifos results in decreased expression of CAT mRNA]; Plant Extracts inhibits the reaction [Chlorpyrifos results in decreased expression of CAT protein]; Polylactic Acid-Polyglycolic Acid Copolymer promotes the reaction [Quercetin inhibits the reaction [Chlorpyrifos results in decreased activity of CAT protein]]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in increased activity of CAT protein]; Quercetin inhibits the reaction [Chlorpyrifos results in decreased activity of CAT protein]; Streptozocin promotes the reaction [Chlorpyrifos results in increased activity of CAT protein] | PMID:27268782 PMID:28373059 PMID:29667781 PMID:30267645 PMID:30497708 PMID:31400774 PMID:31823260 PMID:32096903 PMID:33908150 PMID:34425170 PMID:34678318 PMID:35439518 | Cat | decreases activity | ISO | Cat (Mus musculus) | 6480464 | CTD | Chlorpyrifos results in decreased activity of CAT protein | PMID:32120800 | Cat | decreases expression | ISO | Cat (Mus musculus) | 6480464 | CTD | Chlorpyrifos results in decreased expression of CAT mRNA; Chlorpyrifos results in decreased expression of CAT protein | PMID:32955216 PMID:36152060 | Cat | increases activity | ISO | CAT (Homo sapiens) | 6480464 | CTD | Chlorpyrifos results in increased activity of CAT protein | PMID:23850137 PMID:26257840 | Cat | increases expression | ISO | Cat (Mus musculus) | 6480464 | CTD | Chlorpyrifos results in increased expression of CAT mRNA | PMID:32602772 | Cat | multiple interactions | ISO | CAT (Homo sapiens) | 6480464 | CTD | Acetylcysteine inhibits the reaction [Chlorpyrifos affects the activity of CAT protein] | PMID:26257840 | Cat | multiple interactions | ISO | Cat (Mus musculus) | 6480464 | CTD | [cypermethrin co-treated with Chlorpyrifos] results in decreased activity of CAT protein; Ginsenosides inhibits the reaction [Chlorpyrifos results in decreased expression of CAT protein]; Hydrogen inhibits the reaction [Chlorpyrifos results in decreased expression of CAT mRNA]; Plant Extracts inhibits the reaction [[cypermethrin co-treated with Chlorpyrifos] results in decreased activity of CAT protein]; Plant Extracts inhibits the reaction [Chlorpyrifos results in decreased activity of CAT protein]; Polyphenols inhibits the reaction [Chlorpyrifos results in decreased activity of CAT protein] | PMID:15991261 PMID:32120800 PMID:32955216 PMID:36152060 | | ||||||||||||||||||||||
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