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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2279
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cat
Name: catalase
Acc ID: CHEBI:15891
Term: taurine
Definition: An amino sulfonic acid that is the 2-amino derivative of ethanesulfonic acid. It is a naturally occurring amino acid derived from methionine and cysteine metabolism. An abundant component of fish- and meat-based foods, it has been used as an oral supplement in the treatment of disorders such as cystic fibrosis and hypertension.
Chemical ID: MESH:D013654
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Catmultiple interactionsEXP 6480464CTDmonoisoamyl-2,3-dimercaptosuccinate promotes the reaction [Taurine inhibits the reaction [sodium arsenite results in increased activity of CAT protein]]; Taurine inhibits the reaction [Isotretinoin results in decreased activity of CAT protein]; Taurine inhibits the reaction [Malathion results in decreased activity of CAT protein]; Taurine inhibits the reaction [Methamphetamine results in decreased activity of CAT protein]; Taurine inhibits the reaction [potassium bromate results in decreased activity of CAT protein]; Taurine inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]; Taurine inhibits the reaction [sodium arsenite results in decreased expression of CAT protein]; Taurine inhibits the reaction [sodium arsenite results in increased activity of CAT protein]; Taurine inhibits the reaction [Sodium Fluoride results in decreased activity of CAT protein]PMID:19429265 PMID:19616567 PMID:19672740 PMID:19794907 PMID:23041169 PMID:25213677 PMID:27840156 PMID:28987951 PMID:35906876
Catmultiple interactionsISOCat (Mus musculus)6480464CTDTaurine inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein]; Taurine inhibits the reaction [Potassium Dichromate results in decreased activity of CAT protein]; Taurine inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]PMID:15621940 PMID:17624716 PMID:18414974 PMID:18548748 PMID:18561905
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