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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2275
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:80828
Term: Gastrodin
Definition: A glycoside that has formula C13H18O7.
Chemical ID: MESH:C045345
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3multiple interactionsEXP 6480464CTD2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one affects the reaction [[gastrodin co-treated with rhyncophylline] affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of CASP3 mRNA]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [[gastrodin co-treated with rhyncophylline] affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of CASP3 mRNA]]; [gastrodin co-treated with rhyncophylline] affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of CASP3 mRNA]; gastrodin inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; Lithium Chloride affects the reaction [[gastrodin co-treated with rhyncophylline] affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of CASP3 mRNA]]PMID:33645131 PMID:33764184
Casp3affects activityISOCasp3 (Mus musculus)6480464CTDgastrodin affects the activity of CASP3 proteinPMID:23578476
Casp3multiple interactionsISOCasp3 (Mus musculus)6480464CTDgastrodin inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]PMID:33764184
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