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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2275
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:37454
Term: 9,10-phenanthroquinone
Definition: A phenanthrene that has formula C14H8O2.
Chemical ID: MESH:C005399
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3increases activityISOCASP3 (Homo sapiens)6480464CTD9,10-phenanthrenequinone results in increased activity of CASP3 proteinPMID:25289770 PMID:29108775
Casp3multiple interactionsISOCASP3 (Homo sapiens)6480464CTDAcetylcysteine inhibits the reaction [9,10-phenanthrenequinone results in increased activity of CASP3 protein]PMID:29108775
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