GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp3 | increases cleavage | ISO | Casp3 (Mus musculus) | 6480464 | CTD | chloroacetic acid results in increased cleavage of CASP3 protein | PMID:25451595 | Casp3 | multiple interactions | ISO | Casp3 (Mus musculus) | 6480464 | CTD | chloroacetic acid results in increased cleavage of and results in increased activity of CASP3 protein; HSP90B1 protein promotes the reaction [chloroacetic acid results in increased cleavage of CASP3 protein]; HSPA5 protein promotes the reaction [chloroacetic acid results in increased cleavage of CASP3 protein]; SB 203580 inhibits the reaction [chloroacetic acid results in increased activity of CASP3 protein] | PMID:23103613 PMID:25451595 | | ||||||||||||||||||||||
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