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GENE - TERM ANNOTATION REPORT

RGD ID: 2252
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ddr1
Name: discoidin domain receptor tyrosine kinase 1
Acc ID: GO:0038063
Term: collagen-activated tyrosine kinase receptor signaling pathway
Definition: The series of molecular signals initiated by collagen binding to its receptor on the surface of a target cell where the receptor possesses tyrosine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.
Definition Source(s): GOC:bf, GOC:uh, PMID:15888913, PMID:16626936
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ddr1 IEP 151347403RGD  
Ddr1acts_upstream_of_or_withinISODdr1 (Mus musculus)1624291RGD PMID:10970885

PMID:10970885
Ddr1involved_inISODdr1 (Mus musculus)1624291RGD MGI:3629583 PMID:12065315

MGI:3629583 PMID:12065315
Ddr1involved_inISODDR1 (Homo sapiens)1624291RGD PMID:12065315 PMID:21044884 PMID:9659899

PMID:12065315 PMID:21044884 PMID:9659899
Ddr1involved_inIEAARBA:ARBA000341911600115UniProtGO_REF:0000117

GO_REF:0000117
Ddr1involved_inISSUniProtKB:Q083451600115UniProtGO_REF:0000024

GO_REF:0000024
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