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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2247
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cacna2d1
Name: calcium voltage-gated channel auxiliary subunit alpha2delta 1
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cacna2d1decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of CACNA2D1 mRNAPMID:33387578
Cacna2d1increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of CACNA2D1 mRNAPMID:34747641
Cacna2d1affects expressionISOCacna2d1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of CACNA2D1 mRNAPMID:24680724
Cacna2d1increases expressionISOCacna2d1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of CACNA2D1 mRNAPMID:21354282
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