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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2219
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Brca2
Name: BRCA2, DNA repair associated
Acc ID: CHEBI:35591
Term: pregnenolone 16alpha-carbonitrile
Definition: An aliphatic nitrile that has formula C22H31NO2.
Chemical ID: MESH:D011285
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Brca2multiple interactionsISOBrca2 (Mus musculus)6480464CTD[1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Pregnenolone Carbonitrile] results in increased expression of BRCA2 mRNAPMID:23626729
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