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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2199
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2
Name: BCL2, apoptosis regulator
Acc ID: CHEBI:5063
Term: fipronil
Definition: A racemate comprising equimolar amounts of (R)- and (S)-fipronil.
Chemical ID: MESH:C082360
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2decreases expressionEXP 6480464CTDfipronil results in decreased expression of BCL2 mRNAPMID:34352653 PMID:36916050
Bcl2multiple interactionsEXP 6480464CTDAllopurinol inhibits the reaction [fipronil results in decreased expression of BCL2 mRNA]PMID:36916050
Bcl2decreases expressionISOBCL2 (Homo sapiens)6480464CTDfipronil results in decreased expression of BCL2 proteinPMID:21296133
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