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GENE - TERM ANNOTATION REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: GO:0097192
Term: extrinsic apoptotic signaling pathway in absence of ligand
Definition: The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with withdrawal of a ligand from a cell surface receptor, and ends when the execution phase of apoptosis is triggered.
Definition Source(s): GOC:mtg_apoptosis, PMID:15044679, PMID:20816705
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxacts_upstream_of_or_withinISOBax (Mus musculus)1624291RGDMGI:1097161 MGI:1197519 PMID:15680329 PMID:15967824

PMID:15680329 PMID:15967824
Baxinvolved_inIBAMGI:101769 or MGI:108052 or MGI:1097161 or MGI:1330841 or MGI:88138 or MGI:88139 or MGI:99702 or PANTHER:PTN000135648 or UniProtKB:Q078201600115GO_CentralGO_REF:0000033

GO_REF:0000033
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