GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ar | decreases expression | ISO | AR (Homo sapiens) | 6480464 | CTD | Sodium Selenite results in decreased expression of AR mRNA; Sodium Selenite results in decreased expression of AR protein | PMID:16928829 PMID:18760546 | Ar | multiple interactions | ISO | AR (Homo sapiens) | 6480464 | CTD | [Sodium Selenite results in decreased activity of SP1 protein] which results in decreased expression of AR protein; [Sodium Selenite results in increased expression of JUN protein] which results in decreased activity of AR protein; Acetylcysteine inhibits the reaction [Sodium Selenite results in decreased expression of AR mRNA]; Acetylcysteine inhibits the reaction [Sodium Selenite results in decreased expression of AR protein]; Sodium Selenite inhibits the reaction [IL6 protein results in increased activity of AR protein] | PMID:16928829 PMID:17346688 | | ||||||||||||||||||||||
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