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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2139
Species: Rattus norvegicus
RGD Object: Gene
Symbol: App
Name: amyloid beta precursor protein
Acc ID: CHEBI:28716
Term: palmitoleic acid
Definition: A hexadec-9-enoic acid in which the double bond at position C-9 has cis configuration.
Chemical ID: MESH:C008757
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Appmultiple interactionsISOApp (Mus musculus)6480464CTD[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of palmitoleic acid; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of palmitoleic acid]PMID:39172838
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