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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2129
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Apob
Name: apolipoprotein B
Acc ID: CHEBI:2423
Term: acetylleucyl-leucyl-norleucinal
Definition: A tripeptide composed of N-acetylleucyl, leucyl and norleucinal residues joined in sequence.
Chemical ID: MESH:C063261
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Apobmultiple interactionsISOAPOB (Homo sapiens)6480464CTDacetylleucyl-leucyl-norleucinal inhibits the reaction [4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline results in decreased secretion of APOB protein]; acetylleucyl-leucyl-norleucinal inhibits the reaction [Glucosamine results in decreased expression of and results in decreased secretion of APOB protein]; acetylleucyl-leucyl-norleucinal inhibits the reaction [lactacystin results in decreased expression of and results in decreased secretion of APOB protein]; acetylleucyl-leucyl-norleucinal results in increased expression of and results in increased secretion of APOB proteinPMID:19342510 PMID:19383982
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