Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2087
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aldh1a1
Name: aldehyde dehydrogenase 1 family, member A1
Acc ID: CHEBI:3750
Term: clofibrate
Definition: The ethyl ester of clofibric acid.
Chemical ID: MESH:D002994
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aldh1a1affects expressionEXP 6480464CTDClofibrate affects the expression of ALDH1A1 mRNAPMID:19483382
Aldh1a1increases expressionEXP 6480464CTDClofibrate results in increased expression of ALDH1A1 mRNAPMID:12851107
Aldh1a1increases expressionISOAldh1a1 (Mus musculus)6480464CTDClofibrate results in increased expression of ALDH1A1 mRNAPMID:17585979 PMID:22496397 PMID:23811191
Aldh1a1multiple interactionsISOAldh1a1 (Mus musculus)6480464CTD[Clofibrate co-treated with Acetaminophen] affects the expression of ALDH1A1 mRNA; [Clofibrate results in increased activity of PPARA protein] which results in increased expression of ALDH1A1 mRNA; PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of ALDH1A1 mRNA]; PPARA protein affects the reaction [Clofibrate results in increased expression of ALDH1A1 mRNA]PMID:17585979 PMID:22496397
Go Back to source page   Continue to Ontology report