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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2081
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akt1
Name: AKT serine/threonine kinase 1
Acc ID: CHEBI:33130
Term: aluminium hydroxide
Definition: A member of the aluminium hydroxides that has formula H3AlO3.
Chemical ID: MESH:D000536
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akt1increases expressionISOAKT1 (Homo sapiens)6480464CTDAluminum Hydroxide results in increased expression of AKT1 proteinPMID:37409350
Akt1multiple interactionsISOAKT1 (Homo sapiens)6480464CTD[Tretinoin co-treated with BDNF protein co-treated with Aluminum Hydroxide] results in decreased expression of AKT1 protein; dihydrolipoic acid inhibits the reaction [[Tretinoin co-treated with BDNF protein co-treated with Aluminum Hydroxide] results in decreased expression of AKT1 protein]; dihydrolipoic acid inhibits the reaction [Aluminum Hydroxide results in increased expression of AKT1 protein]PMID:37409350
Akt1multiple interactionsISOAkt1 (Mus musculus)6480464CTD[Ovalbumin co-treated with Aluminum Hydroxide] results in increased phosphorylation of AKT1 protein; dioscin inhibits the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased phosphorylation of AKT1 protein]PMID:35481609
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