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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2081
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akt1
Name: AKT serine/threonine kinase 1
Acc ID: CHEBI:28527
Term: rutin
Definition: A rutinoside that is quercetin with the hydroxy group at position C-3 substituted with glucose and rhamnose sugar groups.
Chemical ID: MESH:D012431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akt1multiple interactionsEXP 6480464CTDRutin inhibits the reaction [Fructose results in decreased phosphorylation of AKT1 protein]PMID:22426011
Akt1multiple interactionsISOAkt1 (Mus musculus)6480464CTDRutin inhibits the reaction [Cisplatin results in decreased phosphorylation of AKT1 protein]PMID:35304134
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