GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ahr | increases activity | EXP | | 6480464 | CTD | benzo(b)fluoranthene results in increased activity of AHR protein | PMID:25500124 PMID:28728110 | Ahr | increases response to substance | EXP | | 6480464 | CTD | AHR results in increased susceptibility to benzo(b)fluoranthene | PMID:17141280 | Ahr | multiple interactions | EXP | | 6480464 | CTD | AHR affects the reaction [benzo(b)fluoranthene results in increased activity of [CCNA2 protein binds to CDK2 protein]]; AHR affects the reaction [benzo(b)fluoranthene results in increased expression of CCNA2 protein]; AHR affects the reaction [benzo(b)fluoranthene results in increased expression of CYP1A1 mRNA]; benzo(b)fluoranthene binds to and results in increased activity of AHR protein | PMID:11525907 PMID:12850102 PMID:17141280 | Ahr | affects response to substance | ISO | Ahr (Mus musculus) | 6480464 | CTD | AHR affects the susceptibility to benzo(b)fluoranthene | PMID:12117779 | Ahr | increases activity | ISO | Ahr (Mus musculus) | 6480464 | CTD | benzo(b)fluoranthene results in increased activity of AHR protein | PMID:12371477 | Ahr | increases expression | ISO | Ahr (Mus musculus) | 6480464 | CTD | benzo(b)fluoranthene results in increased expression of AHR protein | PMID:21392559 | Ahr | multiple interactions | ISO | AHR (Homo sapiens) | 6480464 | CTD | benzo(b)fluoranthene promotes the reaction [AHR protein results in increased expression of CYP1A1 mRNA] | PMID:21781905 | | ||||||||||||||||||||||
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