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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2067
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Agrn
Name: agrin
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Agrndecreases expressionISOAgrn (Mus musculus)6480464CTDsodium arsenite results in decreased expression of AGRN mRNAPMID:37682722
Agrnincreases expressionISOAGRN (Homo sapiens)6480464CTDsodium arsenite results in increased expression of AGRN mRNAPMID:17879257 PMID:34032870
Agrnmultiple interactionsISOAGRN (Homo sapiens)6480464CTD[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of AGRN mRNA; [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of AGRN mRNAPMID:39836092
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