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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2053
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Parp1
Name: poly (ADP-ribose) polymerase 1
Acc ID: CHEBI:50819
Term: ferric oxide
Definition: An iron oxide that has formula Fe2O3.
Chemical ID: MESH:C000499
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Parp1increases cleavageISOPARP1 (Homo sapiens)6480464CTDferric oxide analog results in increased cleavage of PARP1 proteinPMID:27270449
Parp1increases cleavageISOParp1 (Mus musculus)6480464CTDferric oxide results in increased cleavage of PARP1 proteinPMID:26991130
Parp1multiple interactionsISOParp1 (Mus musculus)6480464CTDferric oxide results in decreased expression of and results in increased cleavage of PARP1 proteinPMID:28993115
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