GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Parp1 | increases activity | ISO | Parp1 (Mus musculus) | 6480464 | CTD | zinc chloride results in increased activity of PARP1 protein | PMID:18509044 | Parp1 | increases expression | ISO | Parp1 (Mus musculus) | 6480464 | CTD | zinc chloride results in increased expression of PARP1 protein | PMID:22253048 | Parp1 | increases response to substance | ISO | Parp1 (Mus musculus) | 6480464 | CTD | PARP1 results in increased susceptibility to zinc chloride | PMID:18509044 | Parp1 | multiple interactions | ISO | PARP1 (Homo sapiens) | 6480464 | CTD | zinc chloride inhibits the reaction [cobaltous chloride inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]]; zinc chloride inhibits the reaction [sodium arsenite results in decreased activity of PARP1 protein]; zinc chloride promotes the reaction [Hydrogen Peroxide results in increased activity of PARP1 protein] | PMID:19056730 PMID:19714248 PMID:33645215 | Parp1 | multiple interactions | ISO | Parp1 (Mus musculus) | 6480464 | CTD | 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]; acetovanillone inhibits the reaction [zinc chloride results in increased activity of PARP1 protein]; Cibacron Blue F 3GA inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]; coomassie Brilliant Blue inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased activity of PARP1 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased activity of PARP1 protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of ADGRE1 protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of CSF2 protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1A protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1B protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL3 protein]; periodate-oxidized adenosine 5'-triphosphate inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [zinc chloride results in increased expression of PARP1 protein] | PMID:18509044 PMID:22253048 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |