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GENE - TERM ANNOTATION REPORT

RGD ID: 18931757
Species: Heterocephalus glaber
RGD Object: Gene
Symbol: Comt
Name: catechol-O-methyltransferase
Acc ID: DOID:9004890
Term: Paranoid Disorders
Definition: Chronic mental disorders in which there has been an insidious development of a permanent and unshakeable delusional system (persecutory delusions or delusions of jealousy), accompanied by preservation of clear and orderly thinking. Emotional responses and behavior are consistent with the delusional state.
Definition Source(s): MESH:D010259
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ComtsusceptibilityISOCOMT (Homo sapiens)9068941RGDassociated with cocaine dependence; DNA:SNPs,haplotypes:multiplePMID:21656904 REF_RGD_ID:401940117
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