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GENE - TERM ANNOTATION REPORT

RGD ID: 18920028
Species: Heterocephalus glaber
RGD Object: Gene
Symbol: Kras
Name: KRAS proto-oncogene, GTPase
Acc ID: DOID:0080764
Term: hereditary diffuse gastric cancer
Definition: A diffuse gastric cancer that is characterized by characterized by the development of diffuse (signet ring cell) gastric cancer at a young age, associated with germline heterozygous mutations of CDH1, MAP3K6 and CTNNA1 genes. (DO)
Definition Source(s): https://ghr.nlm.nih.gov/condition/hereditary-diffuse-gastric-cancer "DO" "DO", https://pubmed.ncbi.nlm.nih.gov/20591882/ "DO" "DO", https://rarediseases.info.nih.gov/diseases/10900/disease "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
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