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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1605729
Species: Homo sapiens
RGD Object: Gene
Symbol: HMGB1
Name: high mobility group box 1
Acc ID: CHEBI:34674
Term: dextran sulfate
Definition: A polymer composed of repeating (1->6)-alpha-linked anhydroglucose sulfate units.
Chemical ID: MESH:D016264
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HMGB1multiple interactionsISOHmgb1 (Mus musculus)6480464CTDDextran Sulfate results in increased expression of and results in increased secretion of HMGB1 protein; dihydrotanshinone I inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased secretion of HMGB1 protein]PMID:29496522
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