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GENE - TERM ANNOTATION REPORT

RGD ID: 1604346
Species: Homo sapiens
RGD Object: Gene
Symbol: LYAR
Name: Ly1 antibody reactive
Acc ID: GO:0005730
Term: nucleolus
Definition: A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
Definition Source(s): ISBN:0198506732
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
LYARlocated_inIDA 150520179ARUK-UCL PMID:24495227 PMID:31413131 PMID:31504794

GO_REF:0000052 GO_REF:0000054 PMID:24495227 PMID:31413131 PMID:31504794
LYARlocated_inIEAUniProtKB:Q08288 or ensembl:ENSMUSP00000084791150520179Ensembl GO_REF:0000107
LYARis_active_inIBAMGI:107470 or PANTHER:PTN000318364 or UniProtKB:Q9NX58150520179GO_Central GO_REF:0000033
LYARlocated_inIEAPANTHER:PTHR13100:SF10150520179TreeGrafter GO_REF:0000118
LYARlocated_inIEAUniProtKB-SubCell:SL-0188150520179UniProt GO_REF:0000044
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